Possessing three decades of experience in the pharmaceutical industry, John Klein serves as the chairman of Teaneck, New Jersey-based Cambridge Therapeutics. John Klein is responsible for guiding Cambridge Therapeutics in the development of combination therapies and novel drug delivery systems.
Novel drug delivery systems involve innovative approaches to the delivery of drugs. The process used to deliver drugs to patients can significantly impact their effectiveness and safety. For instance, many pharmaceuticals have an optimum concentration range that provides a maximum amount of therapeutic benefit, while higher amounts can be toxic and lower amounts may result in no benefit.
To maximize the health benefits of pharmaceutical therapies and reduce harmful side effects, researchers are developing new drug delivery systems that are based on interdisciplinary research in fields such as bioconjugate chemistry, polymer science, molecular biology, and pharmaceutics. Some of the techniques used in novel drug delivery systems include cell ghosts, microparticles comprised of biodegradable or insoluble polymers, microcapsules, lipoproteins, soluble polymers, and other delivery techniques.